Pubblicazioni

Prodotti scientifici:
2014.
1) Weight gain reveals dramatic increases in skeletal muscle extracellular matrix remodeling.
Tam CS1, Covington JD, Bajpeyi S, Tchoukalova Y, Burk D, Johannsen DL, Zingaretti CM, Cinti S, Ravussin E.
1Pennington Biomedical Research Center (C.S.T., J.D.C., S.B., Y.T., D.B., D.L.J., E.R.), Baton Rouge, Louisiana 70808; The Charles Perkins Centre and School of Biological Sciences (C.S.T.), University of Sydney, Sydney, 2006 New South Wales, Australia; Department of Kinesiology (S.B.), University of Texas at El Paso, El Paso, Texas 79968; and Department of Experimental and Clinical Medicine-Obesity Center (C.M.Z., S.C.), United Hospitals-University of Ancona, Ancona 60020, Italy.
In: J Clin Endocrinol Metab. 2014 May;99(5):1749-57. doi: 10.1210/jc.2013-4381. Epub 2014 Mar 6.
2) White, brown and pink adipocytes: the extraordinary plasticity of the adipose organ.
 Giordano A1, Smorlesi A, Frontini A, Barbatelli G, Cinti S
1Section of Neuroscience and Cell Biology, Department of Experimental and Clinical Medicine, Università Politecnica delle Marche, Ancona, Italy. 
In: Eur J Endocrinol. 2014 Apr 10;170(5):R159-71. doi: 10.1530/EJE-13-0945. Print 2014.
3) Increased density of inhibitory noradrenergic parenchymal nerve fibers in hypertrophic islets of Langerhans of obese mice
Giannulis I,1* Mondini E,1* Cinti F,1 Frontini A,1 Murano I,1 Barazzoni R,2 Barbatelli G,1Accili D,3 and Cinti S1
1Dpt of Experimental and Clinical Medicine, Obesity Center, University of Ancona (Politecnica delle Marche) and Azienda Ospedali Riuniti, 60020 Ancona, Italy
2Dpt of Medical, Surgical and Health Sciences, Clinical Medicine, University of Trieste, Trieste, Italy
3Naomi Berrie Diabetes Center, Dpt of Medicine, College of Physicians & Surgeons of Columbia University, New York, NY 10032
* These authors contributed equally to this work
In: Nutrition Metabolism and Cardiovascular Disease  2014 Apr, 24(4):384-92.
4) Brown and white adipose tissues: intrinsic differences in gene expression and response to cold exposure in mice.
Rosell M, Kaforou M, Frontini A, Okolo A, Chan YW, Nikolopoulou E, Millership S, Fenech ME, Macintyre D, Turner JO, Moore JD, Blackburn E, Gullick WJ, Cinti S, Montana G, Parker MG, Christian M.
In: Am J Physiol Endocrinol Metab 2014 Apr; 306(8):  945-64
4) Irisin enhances osteoblast differentiation in vitro.
Colaianni G1, Cuscito C1, Mongelli T1, Oranger A1, Mori G2, Brunetti G1, Colucci S1, Cinti S3, Grano M1.Colaianni G, Cuscito
1Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari, 70124 Bari, Italy.
2Department of Clinical and Experimental Medicine, University of Foggia, 71100 Foggia, Italy.
​3Department of Experimental and Clinical Medicine, Center of Obesity, United Hospitals-University of Ancona, 60020 Ancona, Italy.                             In: Int J Endocrinol. 2014;2014:902186. doi: 10.1155/2014/902186. Epub 2014 Mar 4.
5) Fibroblast growth factor-21 is expressed in neonatal and pheochromocytoma-induced adult human brown adipose tissue
Hondares E, Gallego-Escuredo JM, Flachs P, Frontini A, Cereijo R, Goday A, Perugini J, Kopecky P, Giralt M, Cinti S1 ,  Kopecky J, Villaroya F.
1Dpt of Experimental and Clinical Medicine, Obesity Center, University of Ancona (Politecnica delle Marche) and Azienda Ospedali Riuniti, 60020 Ancona, Italy 
In:  Metabolism. 2014 Mar, 63(3): 312-7
 
2013
1) Opposite effects of a high-fat diet and calorie restriction on ciliary neurotrophic factor signaling in the mouse hypothalamus.
Severi I1, Perugini J1, Mondini E1, Smorlesi A1, Frontini A1, Cinti S2, Giordano A1.
1Department of Experimental and Clinical Medicine, Section of Neuroscience and Cell Biology, Università Politecnica delle Marche Ancona, Italy.
2Department of Experimental and Clinical Medicine, Section of Neuroscience and Cell Biology, Università Politecnica delle Marche Ancona, Italy ; Center of Obesity, Università Politecnica delle Marche-United Hospitals Ancona, Italy.
In: Front Neurosci. 2013 Dec 27;7:263. doi: 10.3389/fnins.2013.00263. eCollection 2013. 
2) MicroRNA-26 family is required for human adipogenesis and drives characteristics of brown adipocytes.
Karbiener M1, Pisani DF, Frontini A, Oberreiter LM, Lang E, Vegiopoulos A, Mössenböck K, Bernhardt GA, Mayr T, Hildner F, Grillari J, Ailhaud G, Herzig S, Cinti S, Amri EZ, Scheideler M.
1RNA Biology Group, Institute for Genomics and Bioinformatics, Graz University of Technology, Austria.
In: Stem Cells. 2013 Dec 3. doi: 10.1002/stem.1603. 
3) Adult Epicardial Fat Exhibits Beige Features
Harold S. Sacks, John N. Fain, Suleiman W. Bahouth, Shalini Ojha, Andrea Frontini, Helen Budge, Saverio Cinti,* and Michael E. Symonds*
Endocrinology and Diabetes Division (H.S.S.), VA Greater Los Angeles Healthcare System, Los Angeles, California 90073; 
Department of Medicine (H.S.S.), David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095;
Departments of Microbiology, Immunology, and Biochemistry (J.N.F.) and Pharmacology (S.W.B.), College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38163;
The Early Life Nutrition Research Unit (S.O., H.B., M.E.S.),  Academic Division of Child Health, School of Clinical Sciences, University Hospital, Nottingham NG7 2UH, United Kingdom; and Department of Experimental and Clinical Medicine (A.F., S.C.), Obesity Center, United Hospitals-University of Ancona (Politecnica delle Marche), Ancona 60020, Italy
In : J Clin Endocrinol Metab. 2013 Sep; 98(9):E1448-55.  
4) Obese adipocytes show ultrastructural features of stressed cells and die of pyroptosis.
Giordano A, Murano I, Mondini E, Perugini J, Smorlesi A, Severi I, Barazzoni R, Scherer PE, Cinti S.
Obesity Center, United Hospitals-University of Ancona (Politecnica delle Marche), Ancona 60020, Italy
In:  J Lipid Res. 2013 Sep;54(9):2423-36. 
5) Low FasL levels promote proliferation of human bone marrow-derived mesenchymal stem cells, higher levels inhibit their differentiation into adipocytes
MR Rippo*,1, L Babini1, F Prattichizzo1, L Graciotti1, G Fulgenzi1,2, F Tomassoni Ardori2, F Olivieri1,3, G Borghetti1, S Cinti4, A Poloni5, F Fazioli1 and AD Procopio1,31Laboratory of Experimental Pathology, Department of Clinical and Molecular Sciences, Università  Politecnica delle Marche, Ancona, Italy; 2Neural Development Group, Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, Frederick, MA, USA; 3Center of Clinical Pathology and Innovative Therapies,Italian National Research Center on Aging (INRCA-IRCCS), Ancona, Italy; 4Department of Experimental and Clinical Medicine, Obesity Center, United Hospitals-University of Ancona (Politecnica delle Marche), Ancona , Italy  and 5Clinic of Hematology, Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Italy
In: Cell Death and Disease (2013) 4, e594;  
6) White-to-brown transdifferentiation of omental adipocytes in patients affected by pheochromocytoma
Frontini A,a  Vitali A,a  Perugini J,a  Murano I,a  Romiti C,a  Ricquier D,c  Guerrieri M,a  Cinti S.a,b
a Department of Experimental and Clinical Medicine, Center for the Study of Obesity-United Hospitals University  of Ancona (Politecnica delle Marche), 60126 Ancona, Italy
b The Adipose Organ Lab IRCSS San Raffaele Pisana, 00163 Rome, Italy  
c Université Paris Descartes, CNRS and INSERM Cochin Institute, Paris, France.
In: Biochimicaet Biophysica Acta 1831 (2013) 950-959
 
 
 
 
 
1) Increased density of inhibitory noradrenergic parenchymal nerve fibers in hypertrophic islets of Langerhans of obese mice
 
Giannulis I,1* Mondini E,1* Cinti F,1 Frontini A,1 Murano I,1 Barazzoni R,2 Barbatelli G,1Accili D,3 and Cinti S1
 
1Dpt of Experimental and Clinical Medicine, Obesity Center, University of Ancona (Politecnica delle Marche) and Azienda Ospedali Riuniti, 60020 Ancona, Italy
2Dpt of Medical, Surgical and Health Sciences, Clinical Medicine, University of Trieste, Trieste, Italy
3Naomi Berrie Diabetes Center, Dpt of Medicine, College of Physicians & Surgeons of Columbia University, New York, NY 10032
* These authors contributed equally to this work
 
In: Nutrition Metabolism and Cardiovascular Disease (in press)